Influenza Virus Mashup

Influenza Virus Mashup

Archive for the ‘Internet Flu News’ Category

[Crof's H5N1] WHO on the latest Egyptian H5N1 case

Posted by Automator On July - 29 - 2010

WHO has published Avian influenza - situation in Egypt - update 35.

The Ministry of Health of Egypt has announced a new human case of A(H5N1) avian influenza infection. 

The case is a 20 year-old female from Shobra Elkhima district, Qliubia Governorate. She was admitted to hospital on 21 July, placed on a ventilator, and received oseltamivir treatment. She died on 27 July. 

Investigations into the source of infection indicated that the case had exposure to sick and dead poultry. 

The case was confirmed by the Egyptian Central Public Health Laboratories, a National Influenza Center of the WHO Global Influenza Surveillance Network (GISN). 

Of the 110 laboratory confirmed cases of Avian influenza A(H5N1) reported in Egypt, 35 have been fatal.

[Crof's H5N1] India: Six more H1N1 deaths in Pune

Posted by Automator On July - 29 - 2010

Via The Times of IndiaH1N1 toll 285. Excerpt:

The H1N1 influenza claimed six more lives, taking the death toll in the city to 285. 

According to state health officials, Samuel Prabhakar (70), a resident of Sus road in Pashan, died at the Deenanath Mangeshkar hospital on July 27. Deepali Ratnakar Panchal (7), of Bhosari, died at Unique hospital on July 26. Nivrutti Bhaurao Pawar (44), a resident of Wadkigaon in Haveli, died at the Sassoon Hospital on July 28. Jitendra Dattatray Kasad (42), a resident of Warje Malwadi, died at the Sassoon hospital on July 28. 

Earlier on July 20, Radhika Yashwant Mohite (26), of Hinjewadi, died at Thergaon. A three-and-half-a-year-old boy, Varun, died at the Command Hospital on July 21. 

“The throat-swab reports of most of the patients came late on July 28,” health officials said.

[Avian Flu Diary] Malik Peiris Newspaper Interview

Posted by Automator On July - 29 - 2010

(Wed, 28 Jul 2010 22:36:00 +0000)

 

 

 

# 4764

 

 

 

Malik Peiris is the Chair Professor of Microbiology at The University of Hong Kong, a Virologist at the Queen Mary Hospital and the Scientific Director of the HKU-Pasteur Research Centre at Hong Kong.

 

And if that weren’t enough, he was also one of the genuine heroes of the SARS outbreak in 2003. Peiris and his team were the first to identify the causative agent  (coronavirus) behind that epidemic.

 

You can read a brief profile of Peiris, and Guan Yi -another famed researcher and hero of that crisis - HERE written by Karl Taro Greenfeld.

 

And since I mentioned him, there is probably no better narrative of the SARS outbreak than Karl Taro Greenfeld’s  The China Syndrome: The True Story of the 21st Century’s First Great Epidemic.

 

Today we’ve a long, and informative interview with Professor Peiris appearing in The Hindu newspaper.   It is well worth reading in its entirety.

 

Among the subjects discussed, Peiris argues that trying to make severity a criteria for declaring a pandemic is ill advised.  That it is virtually impossible to gauge the virulence of an influenza virus during the opening months of an outbreak.

 

He also warns that we need to do a better job of surveillance in animals for reassortant viruses, and explains that H5N1 probably has some ways to go before it could ever become adapted to humans. 

 

A hat tip to @CP_Branswell on Twitter for sending this link out.

 

 

Severity should not be part of pandemic criterion

July 29, 2010

 

At a time when the World Health Organisation (WHO) is being criticised for over-reacting and declaring a pandemic of the basis of only geographical spread of a novel flu virus, a leading virologist has argued that severity should not be included as a criterion.

 

Long before WHO’s declaration, there was no doubt that this was a pandemic, observed J.S. Malik Peiris. He leads a multi-disciplinary research programme at the University of Hong Kong, studying emerging viral diseases, including influenza, which spread from animals to humans.

 

“It was a new virus, which we didn’t know about, and [it] swept across the world,” he pointed out at a recent conference on the current pandemic organised by the University of Hong Kong’s Journalism and Media Studies Centre.

 

“If it had been just marginally more severe, we would have been shouting a different tune right now,” he remarked when this correspondent met him after the conference.

(Continue . . . )

[Crof's H5N1] A Brazilian triumph

Posted by Automator On July - 29 - 2010

Via Mauricio’s Precavido.com, an astonishing report from a source called G1: Números da gripe suína (H1N1) estão reduzidos: sinal da vacinação? [Numbers of H1N1 cases are reduced; result of vaccination?] Excerpt, with my translation:

Uma análise preliminar de dados, divulgada pelo Ministério da Saúde nesta quarta-feira (28), aponta que o número de casos graves e de morte causadas pela gripe H1N1 no Brasil caiu entre março e julho, em todas as regiões do País. 

A preliminary analysis reported this Wednesday by the Ministry of Health indicates that the number of serious and fatal cases of H1N1 in Brazil have fallen between March and July in all parts of the country.

Os dados são reunidos de acordo com semanas epidemiológicas. Na semana 10, entre 28 de fevereiro e 6 de março, o país apresentou 79 hospitalizações por conta da doença, o maior número em 2010. 

The data are given by epidemiological weeks. In week 10, between February 28 and March 6, the country had 79 hospitalized H1N1 cases, the highest number in 2010.

Já na semana 28, de 11 a 17 de julho, não houve nenhum registro de internações ligadas à gripe. O ministério também destaca o mesmo padrão quanto ao número de mortes: 11 na semana entre 21 e 27 de fevereiro e nenhuma entre 4 e 17 de julho. 

In week 28, July 11-17, no patients were recorded as hospitalized with flu. The ministry also noted the same pattern in the number of deaths: 11 between February 21 and 27, and none between July 4 and 17.

De acordo com o órgão, os números refletem o impacto da campanha de vacinação realizada no Brasil em 2010, que imunizou 88 milhões de pessoas contra a gripe pandêmica entre 8 de março e 2 de junho.

According to the ministry, the numbers reflect the impact of the vaccination campaign carried out in Brazil in 2010, which immunized 88 million persons against pandemic flu between March 8 and June 2.

Personally, I’m both delighted and gobsmacked by this news. We think of Brazil as samba schools and bossa nova singers. From my glimpse of São Paulo in 2002, I saw a gigantic city where they run elections on computers and the rich commute across town by helicopter. (And the tech support for a computer-based workshop is awesome.)

Still, it’s astounding to think that Brazil, with a population of over 191,000,000, could vaccinate almost half its people in less than three months. 

And it’s even more astounding that our media didn’t even notice. 

(Wed, 28 Jul 2010 13:02:00 +0000)

 

 

 

# 4761

 

 

This morning we are hearing of a 24 year-old sand miner named Yenpa Yenti, from Padang, Indonesia who has died of suspected H5N1 infection. 

 

image

 

Thus far, this appears to be a clinical diagnosis, based on symptomology.  Laboratory confirmation will be required before we can be certain, as there are a number of other infectious diseases that can mimic H5N1. 

 

Ida at BFIC has this translation of an article that appeared in the local newspaper Era Baru.

 

Padang, West Sumatera ::: Bird flu suspect dies

Posted by Ida on July 28, 2010

Padang – A sand miner named Yenpa Yenti (24), resident of Kampung Sawah Taratak Mudiak Muaro Kalaban, Sawah Lunto, West Sumatera, allegedly died of H5N1 infection in M Djamil hospital, Padang, Wednesday (28/7).

 

Victim’s parent, Rosmaniar (60) described her son started to experience high fever and chill of hand and feet on 22 July.

 

Next, Rosmaniar brought Yenti to a local health worker, of where she was recommended to bring her son to Sawah Lunto hospital. Because medical team of Sawah Lunto hospital suspected bird flu infection on Yenti, victim was transferred to M Djamil hospital in Padang.

 

Yenti was admitted to M Djamil hospital on 24 July and placed in special unit until the death on 28 July.

 

Director of M Djamil hospital, Irayanti said Yenti was suspected of having bird flu infection with  symptoms such as fever up to 38℃ and breathing difficulty. Chest x-ray also showed evidence of lung infection. “According to patient’s parents, he had contact with chickens”, added Irayanti.

Yenpa Yenti is first fatal bird flu suspect patient in M Djamil hospital during 2010.

(Continue . . . )

 

 

We are seeing a bit of a an uptick in reporting on cases out of Indonesia in recent weeks.  Whether that reflects more cases, or simply an increased willingness to report on them, is difficult to know.

 

A few blogs concerning Indonesia’s bird flu problem during the month of July include:

 

Another Suspected Bird Flu Fatality In Indonesia
Recent Bengkulu Poultry Deaths Confirmed as H5N1
Forgotten, But Not Gone
Indonesia: MOH Confirms Bird Flu Fatality
Follow Up On Kalimantan Province Report

 

Meanwhile, SAIDR this morning is reporting the sad news that Egypt’s most recent H5N1 infection (see Egypt Announces 110th Bird Flu Case) has died.  My thanks to Lisa at CIDRAP for the head’s up on this report.

  • Date of report: 28 July 2010
  • Governorate: Qalyoubia
  • District: Not reported
  • Event summary: Woman, age not reported, was admitted to a hospital July 21 with bilateral pneumonia and was placed on mechanical ventilation. The MOH reported this was the 110th case of highly pathogenic avian influenza in Egypt in humans and the 35th human death from HPAI.
  • Source of report: Egypt Ministry of Health

[Crof's H5N1] Indonesia: Possible H5N1 death in Sumatera

Posted by Automator On July - 28 - 2010

Via Ida’s Bird Flu Information Corner, a translated report from Era BaruPadang, West Sumatera ::: Bird flu suspect dies. Excerpt:

A sand miner named Yenpa Yenti (24), resident of Kampung Sawah Taratak Mudiak Muaro Kalaban, Sawah Lunto, West Sumatera, allegedly died of H5N1 infection in M Djamil hospital, Padang, Wednesday (28/7). 

Victim’s parent, Rosmaniar (60) described her son started to experience high fever and chill of hand and feet on 22 July. 

Next, Rosmaniar brought Yenti to a local health worker, of where she was recommended to bring her son to Sawah Lunto hospital. Because medical team of Sawah Lunto hospital suspected bird flu infection on Yenti, victim was transferred to M Djamil hospital in Padang. 

Yenti was admitted to M Djamil hospital on 24 July and placed in special unit until the death on 28 July. 

Director of M Djamil hospital, Irayanti said Yenti was suspected of having bird flu infection with  symptoms such as fever up to 38℃ and breathing difficulty. Chest x-ray also showed evidence of lung infection. “According to patient’s parents, he had contact with chickens”, added Irayanti.

[Avian Flu Diary] ASTMH: Dengue and Insect-Borne EIDs In The US

Posted by Automator On July - 28 - 2010

(Wed, 28 Jul 2010 15:39:00 +0000)

 

 

# 4763

 

 

EID’s are Emerging Infectious Diseases, and many are transmitted by mosquitoes and other insect vectors The CDC maintains a website by their DVBID (Division of Vector-Borne Infectious Diseases) that covers many of these emerging pathogens.

 

DVBID Logo

Bacterial
Diseases Branch

Arboviral
Diseases Branch

Dengue
Branch

 

 

Quite a rogues gallery of nasty diseases, many of which are on the comeback trail here in the United States.

 

We’ve a press release from the American Society of Tropical Medicine and Hygiene (ASTMH) expressing deep concern over proposed budget cuts in the CDC’s Division of Vector-Borne Infectious Diseases.

 

 

Dengue Fever and Insect-Borne Infections Emerging as Public Health Problem in Areas of the United States

- Areas of Texas and Florida report recent cases of dengue fever, a virus-based disease spread by mosquitoes -

- The American Society for Tropical Medicine and Hygiene supports continued funding of government programs to detect and control diseases transmitted by insects and ticks, as Obama’s 2011 budget threatens to cut funding -

 

Press Release Source: The American Society of Tropical Medicine and Hygiene On Tuesday July 27, 2010, 2:00 pm EDT

DEERFIELD, Ill., July 27 /PRNewswire/ – Several cases of dengue fever, a potentially fatal viral disease transmitted by the bite of urban dwelling Aedes aegypti and Aedes albopictus mosquitoes, have recently been reported in the continental United States.  Prevalent in Central America and the Caribbean, dengue fever’s most common symptoms include fever, chills, headache, and body aches lasting several days.  The disease’s more threatening form, dengue hemorrhagic fever, can cause internal bleeding, loss of blood pressure, and death. Over the past five years, outbreaks of both forms of the disease have been reported in Texas and Florida.

 

Despite the threat of further introduction of dengue into the mainland United States, as well as the risk of introduction of additional vector-borne diseases, President Obama’s 2011 fiscal budget reduces to zero the funding to support the vector-borne infectious disease program at the Centers for Disease Control and Prevention (CDC), the only national program that focuses of detection and outbreak control of vector-borne diseases including dengue, plague, viral encephalitis and Lyme disease.

 

“At the American Society for Tropical Medicine and Hygiene, we are concerned that the currently proposed 2011 budget would not provide sufficient funding for this important government function.  One in fifty people in the world dies of an illness acquired from an insect bite, and tens of thousands of Americans already fall ill each year from infections transmitted by mosquitoes and ticks.  Insects do not respect state borders, and neither can our national response,” said Edward T. Ryan, M.D., President, American Society of Tropical Medicine and Hygiene (ASTMH).  “Although we recognize and applaud the need to constantly scan the Federal budget to identify outdated or unnecessary programs, eliminating the CDC’s vector-borne infectious disease program is not one of these areas.  The proposed cuts to this program would be shortsighted, and would harm the health of the American people.”

(Continue  . . . .)

 

While I recognize the need to get some control over the ballooning budget, it seems to me that the CDC should be among the last places to make substantial cuts.

[Crof's H5N1] A problem in Indonesia

Posted by Automator On July - 28 - 2010

The Indonesian Ministry of Health has begun reporting on H5N1 cases again, but this Avian Influenza Case Report Until June 2010 reflects its problems. Excerpt:

Throughout May s.d. June 2010 there is one additional positive cases of bird flu (H5N1), on behalf of TFA (34 years, P), residents of Jakarta. Positively infected by H5N1 cases were reported according to the examination Laboratory Research Center for Biomedical and Pharmaceutical Research and Development Agency dated June 4, 2010. Patients with onset of illness on May 25, 2010 with symptoms of fever, cough, shortness of nausea, and muscle aches. Patients treated on May 27 to private practice. A day later to go to private hospitals in Tangerang. During the treatment in hospital, the patient’s condition continued to deteriorate with symptoms of severe pneumonia. June 1, the patient was referred to Tangerang General Hospital and died on the same day.

The main problem is delay. As far as I know, this item was posted fairly recently, and I can’t find anything on the site about more recent cases. (The site is not very navigable.)

The English errors make the report hard to understand, though it’s intelligible if you work at it.

Obviously the ministry’s chief duty is to its own citizens, and the Bahasa Indonesia website may be far more informative and up to date. But when Indonesia is a major focus of H5N1, it ought to be able to put more resources into keeping the rest of the world informed.

(Wed, 28 Jul 2010 10:58:00 +0000)

 

 

# 4760

 

 

We’ve a new study appearing in the BMC Journal that pretty much confirms the polling we’ve seen over the past couple of years on the willingness of  HCWs (Health Care Workers) to work during a severe pandemic.

 

In a severe pandemic – unlike novel H1N1 – the mortality rate would likely approach or perhaps even exceed that seen during the 1918 Spanish Flu.

 

All along, government planners have assumed that up to 40% of HCWs might be absent due to illness or staying home to care for ill family members.

 

There is another category of absenteeism which is less commonly discussed; the unwillingness of some HCWs to report for work in a pandemic.

 

First a look at the abstract to today’s study (slightly reformatted for readability-emphasis mine), which was conducted before the outbreak of novel H1N1, then I’ll return with some additional comments.

 

 

Characterizing hospital workers’ willingness to report to duty in an influenza pandemic through threat- and efficacy-based assessment

 

Ran D Balicer , Daniel J Barnett , Carol B. Thompson , Edbert B. Hsu , Christina L. Catlett , Christopher M. Watson , Natalie L. Semon , Howard S Gwon  and Jonathan M. Links

BMC Public Health 2010, 10:436doi:10.1186/1471-2458-10-436

Published: 26 July 2010

Abstract (provisional)
Background

Hospital-based providers’ willingness to report to work during an influenza pandemic is a critical yet under-studied phenomenon. Witte’s Extended Parallel Process Model (EPPM) has been shown to be useful for understanding adaptive behavior of public health workers to an unknown risk, and thus offers a framework for examining scenario-specific willingness to respond among hospital staff.

Methods

We administered an anonymous online EPPM-based survey about attitudes/beliefs toward emergency response, to all 18,612 employees of the Johns Hopkins Hospital from January to March 2009. Responses were received from 3426 employees (18.4%), approximately one third of whom were health professionals.

Results

Demographic and professional distribution of respondents was similar to all hospital staff. Overall, more than one-in-four (28%) hospital workers indicated they were not willing to respond to an influenza pandemic scenario if asked but not required to do so. Only an additional 10% were willing if required. One-third (32%) of participants reported they would be unwilling to respond in the event of a more severe pandemic influenza scenario.

 

These response rates were consistent across different departments, and were one-third lower among nurses as compared with physicians. Respondents who were hesitant to agree to work additional hours when required were 17 times more likely to be unwilling to respond during a pandemic if asked. Sixty percent of the workers perceived their peers as likely to report to work in such an emergency, and were ten times more likely than others to do so themselves. Hospital employees with a perception of high efficacy had 5.8 times higher declared rates of willingness to respond to an influenza pandemic.

Conclusions

Significant gaps exist in hospital workers’ willingness to respond, and the EPPM is a useful framework to assess these gaps. Several attitudinal indicators can help to identify hospital employees unlikely to respond.

 

The findings point to certain hospital-based communication and training strategies to boost employees’ response willingness, including promoting pre-event plans for home-based dependents; ensuring adequate supplies of personal protective equipment, vaccines and antiviral drugs for all hospital employees; and establishing a subjective norm of awareness and preparedness.

The complete article is available as a provisional PDF. The fully formatted PDF and HTML versions are in production.

 

According to this study, 1/3rd of HCWs would be unwilling to work during a severe pandemic, which corresponds pretty closely to other studies we’ve seen.

 

Lest anyone think working at a hospital or clinic during a severe pandemic would be an easy decision, the hospital worker would be not only repeatedly exposing themselves to the virus, many would also be exposing their families by proxy.

 

Vaccines, antivirals, and even PPEs (Personal Protective Equipment) may be in short supply (or non-existent), and there may be hospital security issues as well.  Some HCWs fear being `locked down’ or quarantined at their facility and unable to go home and care for their own families.

 

And given the expected absenteeism levels and the high rate of admissions, the burden on the remaining staff would be enormous.  

 

And it isn’t just doctors, nurses, and techs. 

 

Non-medical employees such as housekeeping, food service, laundry, security, lab, and even clerical workers are vitally important, and few facilities could operate for very long without them.

 

You’ll find results from similar surveys taken in 2008 and 2009 in the following blogs entries.

 

And The New Survey Says . . .
Will GP’s Work In A Pandemic?

Australia: Will Doctors Work In A Pandemic?

Pandemic Issues For Home Health Providers - Pt 3

Catching Up With The Nurses Poll 

 

 

Since April of 2008 the Allnurses.com forum has been conducting an online poll - asking if nurses would work without full protective PPE’s (Personal Protective Equipment - masks, gowns, gloves, etc.) during a `bird flu’ pandemic.

 

There are now more than 600 comments, and over 8700 respondents to the poll.  

 

Prior to the outbreak of novel H1N1, the percentage of respondents saying they would not report for work was roughly 30%, with another 20% undecided.

 

image

 

In the wake of our current (relatively mild) pandemic, the percentage of those unwilling to work has dropped to just under 22%, with nearly 15% undecided.

 

The vigorous debate in the comments thread  should be required reading for every hospital pandemic coordinator.

 

As this latest study and many of the comments on the allnurses.com thread point out, addressing employee concerns over the availability of antivirals, PPEs,  and vaccines - along with visibly planning for the safety of employees and their families – are critical steps necessary if hospitals hope to retain much of their staff during a severe pandemic.

 

Steps that few hospitals, right now, appear to be taking.

Via Radio New Zealand News: First suspected swine flu death in Northland. Excerpt:

Health authorities in Northland have reported the first ever suspected swine flu death in the region. 

They say a 51-year-old man, who died suddenly earlier in July, was found to have the H1N1 virus. His death has been referred to the coroner. 

Medical Officer of Health Jonathan Jarman says the man had an underlying health condition. 

Dr Jarman says he has been asked about the safety of open casket tangi practices in deaths associated with H1N1 virus. 

Dr Jarman says the virus does not survive long after a person’s death and there is no reason why mourners should not touch or hold the body, or tupapaku, as long as they wash their hands afterwards.