Influenza Virus Mashup

Influenza Virus Mashup

Archive for February, 2010

The Ministry of Health on Sunday said that the total cases of infection, “H 1 – to 1″ was known as swine flu since it appeared in Egypt and even now is 16116, including 5597 cases among school students and 863 cases among college students.

A statement by the Ministry of Health that the total casualties among school students in the past week amounted to only 5 cases among university students and a single case.

The statement noted that the total casualties outside schools and universities was the case, with a total 9656 cases of recovery from the injuries amounted to 15838 healing and the case is still under treatment, 7 cases receiving treatment in hospital.

The statement noted that the total deaths since the outbreak of the disease and so far amounted to 271 cases.

http://www.egynews.net

Two cases of bird flu in Kafr El-Sheikh
Department of Health announced the Kafr El-Sheikh on injured: Zainab Abdul Aziz Al Haddad (30 years), Mohamed Abdullah Mohamed al-Sayed (13 years) infected with avian flu, fever hospital was Hdzhma Kafr El-Sheikh
The Directorate: that their samples are positive, and that brings the number of cases at the level of the Republic to 102 cases since the outbreak of the disease until now.
On the other hand announced that the Directorate of Veterinary Medicine, Kafr El-Sheikh 8900 execution of an infected bird with various illnesses, and the closure of 25 poultry farms do not comply, the closure of 9 shops for the birds in Kafr El-Sheikh and Desouk; for non-compliance with the specifications.
It was also editor of 100 cases of butcher shops in all centers to maintain; to slaughter outside Alskhanp.
http://www.dowell-netherlands.com/2010/02/two-cases-of-bird-flu-in-kafr-el-sheikh.html

Barbados
• Barbados becoming diagnostic lab capital (Link)

Bhutan
• Measures to control bird flu (Link)
• OIE report on outbreak of H5N1 in Bhutan (Link)

Vietnam
• ProMED: Vietnam’s 1st H5N1 fatality of 2010 (Link)

Commentary
• Daily Kos: Paid Sick Days – Interview With Jon Green (Link)

[Crof's H5N1] New Zealand promotes flu "super-shot"

Posted by Automator On February - 28 - 2010

While we try to forget H1N1, the people in the southern hemisphere are trying to prevent a new wave. Via the Wairarapa Times-AgeNew shots fired in flu fight - Local News. Excerpt:

A new influenza super-shot will hopefully keep pregnant women, the chronically sick, and elderly people shielded against swine flu in Wairarapa this year. 

The at-risk groups are being targeted from Monday in an early immunisation campaign, but immunisations will also be available to paying customers. 

The improved seasonal influenza vaccine, at GP practices from Monday, will cover recipients against the H1N1 (swine) flu strain, as well as two other strains of influenza prevalent in California and Asia. Swine flu killed 16,000 people worldwide last year. 

The shot will also be aimed at some children with high needs as well as people who are obese, aged over 65, or have chronic illnesses.
It works in the same way as other influenza vaccines and following immunisation takes about two weeks to build a good immune response, say specialists. 

There were still stocks of the antiviral medicine Tamiflu in the region, but it was expected the new vaccine would mean little of that would be needed.

[Crof's H5N1] Australia: Manunda swine-flu sufferer urges vaccination

Posted by Automator On February - 28 - 2010

Via Cairns.com.au: Manunda swine-flu sufferer urges vaccination. Excerpt:

Swine flu sufferer Zac Forster wouldn’t wish the virus he caught late last year on anybody. 

The 23-year-old from Manunda was one of the hundreds of Cairns residents who contracted the virus last year.

During the first wave of the pandemic last year, 41 Queenslanders died from swine flu including seven people in Cairns. 

In Zac’s case, H1N1 left him bed-ridden for two weeks.
“I was still feeling the effects for some time,” Zac said. “I had aches and pains all over and kept having hot and cold flushes.” 

Only 15 per cent of Far Northern residents have been vaccinated against swine flu and doctors fear the region may be ill-equipped for future outbreaks. Another wave is expected by the end of March. 

Zac, who is now vaccinated against the H1N1 human swine influenza, said it was important for everyone to be vaccinated against the virus. 

“The pain I went through having this virus, it’s not worth not being
vaccinated,” he said.

[Crof's H5N1] Paid sick days: A lesson from H1N1

Posted by Automator On February - 28 - 2010

DemFromCT has a new item on Daily Kos: Paid sick days: Interview with Jon Green. Excerpt:

As we watch the battle over health reform play out against the backdrop of an H1N1 pandemic, I am reminded of many of the political lessons learned over the years (”don’t get mad, organize”, “all politics is local”) including the exhortations of many posters here (”are you going to complain, or are you going to do something?”) to work for change, real change that you can measure and see and feel. 

As it happens, my home state of Connecticut is also home to a campaign to improve ordinary people’s lives by highlighting a local legislative battle to mandate paid sick days for employers of larger companies. This is legislation that’s come close to passing before (it’s passed each chamber, but not in the same year), and this year, there’s a concerted push to get it done. 

Who doesn’t have paid sick days? Among others, day care and nursing home workers, bus drivers, grocery workers and very likely your neighbors or someone you know. And from a societal and public health perspective, coming to work sick for these folks is a great way, for example, to spread flu and other illnesses, exactly what you don’t want.

[Avian Flu Diary] Study: Ferrets, H1N1 and Pneumonia

Posted by Automator On February - 28 - 2010

(Sun, 28 Feb 2010 18:20:00 +0000)

 

 

 

# 4392

 

 

While the pandemic of 2009 certainly appears to have been less severe than the 1957 Asian flu, its true impact has not been determined.  

 

It may take months, or perhaps years, before we have a really good handle on the severity of this virus.

 

Despite attempts by some to paint this virus as `no worse than seasonal flu’, we continue to see evidence that novel H1N1 differed from seasonal flu in terms of severity and the profile of patients hardest hit.

 

In a normal flu season, it is those over the age of 65 who make up 90% of the flu-related fatalities.  During the past 10 months, those under 65 have borne the brunt of this virus.

 

While the vast majority of those infected by this virus only suffered mild to moderate illness, a significant number number of people suffered serious complications.   In many cases, those victims developed severe, life threatening pneumonias.

 

Over the past eight months we’ve seen a steady parade of reports showing that there is something fundamentally different about the way the novel H1N1 virus attacks humans.   

 

A few blogs on that subject include:

 

Canada: H1N1 Sent More To ICU Than Seasonal Flu
I Only Have Eyes For Flu
Cytokine Storm Warnings
NIH: Post Mortem Studies Of H1N1
Pathology Of Fatal H1N1 Lung Infections

 

Today we’ve another study, this time out of the Department of Virology, Erasmus Medical Centre and ViroClinics Biosciences BV, Rotterdam, The Netherlands  which uses a ferret model to test the pathogenicity of the novel H1N1 virus against seasonal and bird flu.

 

Ferrets are often used in influenza studies due to their high susceptibility to the virus.

 

The entire study is a pay-per-view in the latest edition of The Journal of Infectious Diseases, so I only have access to the abstract.  

 

If this study sounds familiar, there’s a reason.

 

This appears to be a follow up to research widely reported last summer (see The ECDC On The Ferret Pathogenicity Study, and Ferreting Out The Severity Of A Flu Virus) on the pathogenesis of novel H1N1 in ferrets.

 

The upshot, once again, seems to indicate that the novel H1N1 virus produces more severe pneumonia (in ferrets) than seasonal flu, although less severe than what is seen from the H5N1 virus.

 

The abstract follows:

 

Severity of Pneumonia Due to New H1N1 Influenza Virus in Ferrets Is Intermediate between That Due to Seasonal H1N1 Virus and Highly Pathogenic Avian Influenza H5N1 Virus

Judith M. A. van den Brand,Koert J. Stittelaar, Geert van Amerongen,Guus F. Rimmelzwaan, James Simon, Emmie de Wit, Vincent Munster,Theo Bestebroer, Ron A. M. Fouchier, Thijs Kuiken, and Albert D. M. E. Osterhaus

 

Background.

The newly emerged influenza A(H1N1) virus (new H1N1 virus) is causing the first influenza pandemic of this century. Three influenza pandemics of the previous century caused variable mortality, which largely depended on the development of severe pneumonia. However, the ability of the new H1N1 virus to cause pneumonia is poorly understood.

 

Methods.

The new H1N1 virus was inoculated intratracheally into ferrets. Its ability to cause pneumonia was compared with that of seasonal influenza H1N1 virus and highly pathogenic avian influenza (HPAI) H5N1 virus by using clinical, virological, and pathological analyses.

 

Results.

Our results showed that the new H1N1 virus causes pneumonia in ferrets intermediate in severity between that caused by seasonal H1N1 virus and by HPAI H5N1 virus. The new H1N1 virus replicated well throughout the lower respiratory tract and more extensively than did both seasonal H1N1 virus (which replicated mainly in the bronchi) and HPAI H5N1 virus (which replicated mainly in the alveoli). High loads of new H1N1 virus in lung tissue were associated with diffuse alveolar damage and mortality.

 

Conclusions.

The new H1N1 virus may be intrinsically more pathogenic for humans than is seasonal H1N1 virus.

[Crof's H5N1] Cuba: Teenager recovers from H1N1

Posted by Automator On February - 28 - 2010

Thanks to the reader who sent the link to this Cuban News Agency report: Cuban Teen Thanks Doctors for Recovery from A (H1N1). Excerpt:

A 13-year-old girl, Claudia Nery Toro Conde, thanked the doctors that treated her after catching the influenza A (H1N1), as well as her parents and professors, who played an important role in her fast recovery. 

Her teachers became aware of the possible disease at the school when the teen referred about having a headache and a sore throat, besides high fever and her nose was running constantly. 

Right away she was suspended from school and her parents were informed on the situation, while the family doctor and the Eduardo Agramonte Piña Children Hospital provided specialized advises on how to deal with the case. 

Claudia was home-hospitalized for 15 days after a throat exudates performed on her confirmed the disease. “The medical attention was very good, the family doctor and the nurse were coming every day to my house to find out how I was doing”, recalls Claudia. 

Her mother, Barbara, told ACN news agency about the measures they took at home, such as keeping the house clean, washing sheets and clothes on daily basis, while preventing people from coming in and the girl coming out, in order to avoid the influenza to spread. 

Barbara thanked the Cuban revolution for the doctors’ care, who visited them every afternoon, as well as the teachers; and all that without having to pay a dime.

[Avian Flu Diary] Roundup Of Flublogia

Posted by Automator On February - 28 - 2010

(Sun, 28 Feb 2010 14:47:00 +0000)

 

 

# 4391

 

 

It’s been several weeks since my last recap of stories from in and around Flublogia (along with other science blogs), so this quiet Sunday morning seems an ideal time to catch up.

 

As always, this is a subjective list of things that I found of interest, and by no means mentions every worthy blog post out there.

 

With influenza on the decline in North America and around the world, much of the focus of Flublogia has shifted away from `breaking news’ to a review of what we’ve learned, or are learning, from this pandemic.

 

You’ll also find a rise in coverage of other EIDs (Emerging Infectious Diseases).

 

My apologies for the good stories I may miss.  So, with that said, in no particularly order . . .

 

 

CIDRAP has a long history of providing in depth coverage of EIDs and other pathogenic threats.   Their frequently updated Novel H1N1 Influenza (Swine Flu) overview is a resource I use on a regular basis.

 

CIDRAP News coverage is second to none, with terrific reporting by editor Robert Roos, staff writer Lisa Schnirring, and contributing writer Maryn McKenna.  

 

A few recent examples include:

 

Hong Kong reports swine-pandemic flu reassortant 

Emergency departments see rise in flu-like illness

Study yields highly pathogenic avian, human flu virus mix

Updated review questions benefits of flu vaccine in elderly

 

If CIDRAP News isn’t among your daily internet stops (they update weekdays - usually late afternoon/early evening EST), it should be.

 

While H1N1 may be declining, H5N1 bird flu reports have been on the rise, with both human and poultry infections reported in places like Indonesia, Vietnam, and Egypt.  

 

Often, we get our first glimpse of these cases from the flu forum newshounds who work diligently each and every day, combing through foreign language media for these sorts of reports. 

 

This is exacting (and sometimes exhausting) work, and it requires both dedication and skill.   You’ll find a tribute to these volunteers in my essay: Newshounds: They Cover The Pandemic Front.

 

I won’t attempt to name them all, but the four whose names seem to be showing up the most in this blog over the past few weeks are; Ironorehopper, Dutchy, Ida at BFIC, and Commonground of Pandemic Information News.

 

My thanks to them, and to all of the other newshounds.

 

Sharon Sanders, editor of FluTrackers conducted another in her series of high profile radio interviews last week, this time with Gregory Härtl, spokesperson for the World Health Organization.  

 

If you missed the broadcast, the show is archived here.

 

My buddy Scott McPherson doesn’t blog as often as most of us would like, but when he does it is invariably an informative, and always entertaining, read.   You’ll find three new blogs this month on his website.

 

The countdown to the release of Maryn McKenna’s new book  SUPERBUG: The Fatal Menace of MRSA continues, with the big day just over 3 weeks away

 

Meanwhile, Maryn continues to update us on emerging antibiotic resistant pathogens via her Superbug blog, with several stories that showcased the reports from CBS Evening News with Katie Couric on the use of antibiotics on the farm.

 

CBS antibiotics and farming package, day one
CBS antibiotics and farming, day 2 - and more on the Danish experience
Antibiotics and farming — CBS follow-up video

 

Revere at Effect Measure is drowning writing a grant proposal, but still manages to come up for air on occasion.  Recently Revere looked at the issue of pre-existing conditions and pandemic influenza in Bad flu and underlying medical conditions.

 

Crof over at Crofsblog, is using his Spanish language skills to track emerging infectious diseases in Central and South America, along with his usual terrific coverage of influenza.  You’ll find some of the best coverage of Dengue, Malaria, and other diseases on his blog.

 

Ian York on his Mystery Rays blog continues to fascinate with his historical look back at disease outbreaks of the past, including his recent look at yellow fever (The deadliest, most awe-inspiring of the Plagues ).

 

Prior to that Ian looked at the complex issues of virulence and transmission in an intriguing look at Rabbits, virulence, history, and connections .

 

On the flu front, York `did the math’ and came up with a reasonable approximation on the level of herd immunity we likely have in the United States to novel H1N1 in How many Americans are immune to H1N1?

 

Paul over at Chen Qi continues to publish – in newspaper format – a terrific daily roundup of disease and disaster news. 

 

Vincent Racaniello at the Virology Blog continues with his series of college virology lectures (#10 is now posted), along with his TWiV and TWiP podcasts.  

 

And of course, the flu forums (I visit Flu Wiki and FluTrackers on a daily basis) continue to provide a font of information.

 

 

A sampling of some of my own offerings would include:

 

Influenza B Rising
Assessing A New Antiviral
PNAS: H3N2 And H5N1 Reassortment
Norovirus: The Gift That Keeps On Giving
An H1N1 Seroprevalence Study
TCAD: A Triple Play Combination
H9N2: The Other Bird Flu Threat

 

 

Hopefully this roundup will point you towards an article, or perhaps a resource, you may have missed in the past.

[Pandemic Flu Central] Egypt: H1N1 total now 271

Posted by Automator On February - 27 - 2010

The third case in 6 days and total about 271 The death of a woman at the age of 31 years of swine flu in Egypt The Ministry of Health in Egypt Saturday by the death of new cases infected with e “1 HP 1 The” world-renowned swine flu, bringing the total deaths in Egypt since the emergence of the disease and so far 271 cases. A statement by the Ministry of Health that the new death of a woman from the province Alascdndrip at the age of 31 years and is this is the case Aiipkhalal six days. This has been the World Health Organization announced on 23 January to January to swine flu virus is moving towards recession in Egypt, are likely to be the peak of the disease in Egypt recorded the beginning of January.

 http://www.egynews.net/

Bhutan
Bird Flu Containment Update (Link)

Canada
• Canadian scientists use Olympics to study spread of infectious diseases (Link)

United States
• CA: 11th swine flu death in Sonoma County (Link)
• GA: Swine flu vaccines go unused (Link)

Vietnam
• First bird flu fatality for 2010 (Link)
• Animal disease warning issued as bird flu kills Mekong resident (Link)

General
• CIDRAP: FDA approves 13-valent pneumococcal vaccine (Link)
• Hyping H1N1: Did It Create a Dangerous Flu Fatigue? (Link)

Commentary
• Recombinomics: Widespread and Common Tamiflu Resistance in Japan (Link)

[Pandemic Flu Central] Egypt: H1N1 total now 271

Posted by Automator On February - 27 - 2010

The third case in 6 days and total about 271 The death of a woman at the age of 31 years of swine flu in Egypt The Ministry of Health in Egypt Saturday by the death of new cases infected with e “1 HP 1 The” world-renowned swine flu, bringing the total deaths in Egypt since the emergence of the disease and so far 271 cases. A statement by the Ministry of Health that the new death of a woman from the province Alascdndrip at the age of 31 years and is this is the case Aiipkhalal six days. This has been the World Health Organization announced on 23 January to January to swine flu virus is moving towards recession in Egypt, are likely to be the peak of the disease in Egypt recorded the beginning of January.

 http://www.egynews.net/

Bhutan
Bird Flu Containment Update (Link)

Canada
• Canadian scientists use Olympics to study spread of infectious diseases (Link)

United States
• CA: 11th swine flu death in Sonoma County (Link)
• GA: Swine flu vaccines go unused (Link)

Vietnam
• First bird flu fatality for 2010 (Link)
• Animal disease warning issued as bird flu kills Mekong resident (Link)

General
• CIDRAP: FDA approves 13-valent pneumococcal vaccine (Link)
• Hyping H1N1: Did It Create a Dangerous Flu Fatigue? (Link)

Commentary
• Recombinomics: Widespread and Common Tamiflu Resistance in Japan (Link)

[Pandemic Flu Central] Egypt: H1N1 total now 271

Posted by Automator On February - 27 - 2010

The third case in 6 days and total about 271 The death of a woman at the age of 31 years of swine flu in Egypt The Ministry of Health in Egypt Saturday by the death of new cases infected with e “1 HP 1 The” world-renowned swine flu, bringing the total deaths in Egypt since the emergence of the disease and so far 271 cases. A statement by the Ministry of Health that the new death of a woman from the province Alascdndrip at the age of 31 years and is this is the case Aiipkhalal six days. This has been the World Health Organization announced on 23 January to January to swine flu virus is moving towards recession in Egypt, are likely to be the peak of the disease in Egypt recorded the beginning of January.

 http://www.egynews.net/

Bhutan
Bird Flu Containment Update (Link)

Canada
• Canadian scientists use Olympics to study spread of infectious diseases (Link)

United States
• CA: 11th swine flu death in Sonoma County (Link)
• GA: Swine flu vaccines go unused (Link)

Vietnam
• First bird flu fatality for 2010 (Link)
• Animal disease warning issued as bird flu kills Mekong resident (Link)

General
• CIDRAP: FDA approves 13-valent pneumococcal vaccine (Link)
• Hyping H1N1: Did It Create a Dangerous Flu Fatigue? (Link)

Commentary
• Recombinomics: Widespread and Common Tamiflu Resistance in Japan (Link)